• Hollywood Actress Award - Hollywood Film Festival (2012)
for 'De rouille et d'os' (Rust & Bone)

• Silver Medallion Award - Telluride Film Festival (2012)
for 'De rouille et d'os' (Rust & Bone)

• Desert Palm Achievement Actress Award - Palm Springs Film Festival (2010)
for 'Nine'

• Oscar - Academy Awards (2008)
Best Performance by an Actress in a Leading Role for 'La Môme' (La Vie en Rose)

• BAFTA Film Award - British Academy of Film & Television Arts Awards (2008)
Best Leading Actress for 'La Môme' (La Vie en Rose)

• London Critics Circle Award - London Critics Circle (2008)
Actress of the Year for 'La Môme' (La Vie en Rose)

• Golden Globe - Golden Globes (2008)
Best Performance by an Actress in a Motion Picture – Comedy or Muscial for 'La Môme' (La Vie en Rose)

• Breakthrough Performance Award - Palm Springs Film Festival (2008)
for 'La Môme' (La Vie en Rose)

• Virtuosos Award - Santa Barbara Film Festival (2008)
for 'La Môme' (La Vie en Rose)

• African-American Film Critics Association (2007)
Best Actress for 'La Môme' (La Vie en Rose)

• Satellite Award - Satellite Awards (2007)
Best Actress in a Motion Picture, Drama for 'La Môme' (La Vie en Rose)

• Los Angeles Film Critics Association (2007)
Best Actress for 'La Môme' (La Vie en Rose)

• Boston Society of Film Critics (2007)
Best Actress for 'La Môme' (La Vie en Rose)

• Hollywood Actress Award - Hollywood Film Festival (2007)
for 'La Môme' (La Vie en Rose)

• NRJ Ciné Award - NRJ Ciné Awards (2007)
Frenchie of the Year for 'La Môme' (La Vie en Rose)

• NRJ Ciné Award - NRJ Ciné Awards (2007)
Best Look for 'La Môme' (La Vie en Rose)

• Swann d'or - Cabourg Romantic Film Festival (2007)
Best Actress for 'La Môme' (La Vie en Rose)

• César Award - César Awards (2005)
Best Supporting Actress for 'Un long dimanche de fiançailles' (A Very Long Engagement)

• Chopard Trophy - Cannes Film Festival (2004)
Female Revelation

• Jury Award - Newport Beach Film Festival (2004)
Feature Film - Best Actress - Drama for 'Jeux d'Enfants' (Love Me If You Dare)

• Verona Love Screens Film Festival (2001)
Best Actress for 'Lisa'

• Swann d'or - Cabourg Romantic Film Festival (2000)
Best New Actress for 'Taxi 2'

• Festival d’Autrans (1999)
Best Actress for 'La Guerre dans le Haut Pays' (War in the Highlands)

• Conservatoire d'Orléans (1994)
Premier Prix

Nominations

• Critics Choice Award - Broadcast Film Critics Association (2010)
Best Supporting Actress for 'Nine'

• St. Louis Gateway Film Critics Association (2009)
Best Supporting Actress (runner-up) for 'Nine'

• Satellite Award - Annual Satellite Awards (2009)
Best Actress (Comedy Or Musical) for 'Nine'

• Detroit Film Critics Society (2009)
Best Supporting Actress for 'Nine'

• Screen Actors Guild Award - Screen Actors Guild Awards (2008)
Outstanding Performance by a Female Actor in a Leading Role for 'La Môme' (La Vie en Rose)

• Critics Choice Award - Broadcast Film Critics Association (2008)
Best Actress for 'La Môme' (La Vie en Rose)

• St. Louis Gateway Film Critics Association (2007)
Best Actress for 'La Môme' (La Vie en Rose)

• Detroit Film Critics Society (2007)
Best Actress for 'La Môme' (La Vie en Rose)

• Dallas Fort-Worth Critics (2007)
2nd Place, Best Actress for 'La Môme' (La Vie en Rose)

• Chicago Film Critics Association (2007)
Best Actress for 'La Môme' (La Vie en Rose)

• European Film Award - European Film Awards (2007)
European Actress 2007 for 'La Môme' (La Vie en Rose)

• César Award - César Awards (2002)
Most Promising Actress for 'Les Jolies Choses' (Pretty Things)

• César Award - César Awards (1999)
Most Promising Actress for 'Taxi'